Multiple Sclerosis Project

Multiple Sclerosis (MS) is a chronic disabling disease that attacks the central nervous system. Disease progression, severity and specific symptoms are unpredictable and vary from one patient to another. Generally, the process of diagnosing MS involves; obtaining evidence from patient history, clinical examinations, a variety of laboratory tests and magnetic resonance imaging (MRI) scans. The traditional treatment for MS has limited effectiveness. The ideal treatment for MS should involve both attenuation of inflammatory responses and induction of tissue protection/regeneration within the Central Nervous System (CNS).

Stem cell based therapy is considered promising for the treatment of MS using autologous Mesenchymal Stem Cells (MSCs); the major mechanism of action of MSCs therapy is to inhibit various components of the immune system that contribute to tissue damage. MSCs can access the CNS where they can provide protection against tissue damage and may facilitate tissue regeneration.

Objectives

Assess the safety of injecting auotologous MSCs to MS patients who fail to respond to conventional treatment.

Assess the therapeutic benefits on MS patients after injection .​


The project has been running for the last 3 years and hasbeen completed. Preliminary analysis showed disease stability and encouraging results with good safety. The project is supported by the University of Jordan.​ We are preparing to initiated a second different source of stem cells and recruiting more patients

For more details please visit  the link: 

http://www.clinicaltrials.gov/ct2/show/NCT01895439?term=MS+stem+cells+Jordan&rank=1

  

 

Cell Therapy Center

"The Use of Human Stem Cells for Therapeutic Purposes"